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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd395c9265895594fbb8a287b408c3242c07c3bbbd70109def6189c87eee2fee0' 
  AND token = 'REjbWqyw2KLnTUttu3sWGIY+Mj4fe6aWBcBLf/fkIVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}