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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f96a234f9828164e0e50c12bbf32da061377e07225979c7bca4cc10fa3ca6b1c' 
  AND token = 'UddzZ+BMiP7exieCiAtlzTiuEvonHXPzNY0E0W7n8Ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}