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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44b416f029dce7a979d2e5582a1de6758e3f172dc08921552e0a525d0812f8df' 
  AND token = 'k4nwsaUisR/1B08CXT5XR/NZZFhIqc/V35dDtxtTYLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}