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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73a048151d6990af3360b81e03d38b1a5a60da7568b5431edde57b773fac6ecc' 
  AND token = 'o0rqHWjgX0aHeI69/b+KGBgJhdRkBS4E21EQVPLdujM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}