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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07074194d01602db251a57c4014eba001940fe8f6da46cc4c928a0484ac13d5f' 
  AND token = 'QS0wKPHKh+OiiX1KOUVHgU4hQYFWW3+l2OTc6Jt8AJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}