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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fd2792075a0067076f570c9af272c5ace536a1d25f161cb4b13d1f1001a3be4' 
  AND token = 'oG0Y/B7w0BEr5+kznO0G98/kQ0fTnooXCiLKN4bkd+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}