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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4097a7c366e5a159de3c5ee2fc68d107f5aa1a5ec62c8190e8fcce44669e265' 
  AND token = 'R2XfGk51D7Ax+m0u/BPGOj5pjuEY7D5KfrXNrdTF6d4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}