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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e7a01015e6de225252f9640d92e8ba45d6bc441b037612e4e722b5b947d5f0b' 
  AND token = 'd2YUyIgjNOXNcL/Le1ML7lHftD4biGtnfG03WHp4b2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}