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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3723a83ac1de506eac828c27fb24f0226102b0f171b9284c610f6d57022eb171' 
  AND token = 'HwBzNkQwXoxB6f3u+TffRrQ+cRIQw9TXLHMiDKlhtWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}