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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c43213d54d512070bc2c78e2e304244ad8841b14c3905b9dfd130ec0c29bc94e' 
  AND token = 'eds4ootkcQzhk1wY4HIgFs7wgduE57f/jQkwBHUomIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}