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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3b2728e646f2c2ead775365858bf01f420eaa3a3e2fc0feac2db9b1c80a3413' 
  AND token = '7Degs425+e0FbWpVUSyWoPH8x3Gi9t0b1A6WW+x7Vjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}