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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc6b61c75aee6228f586d166023b966923439a935d09512d2dec758ab1454259' 
  AND token = 'PiYVuTR2bZXAlwm4P/49YDM/gmPgHF2lNc4RSYlv7OI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}