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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05b17ad98917886050c33e34b2a5131a7802beabc1fbf789fbca1247247e843f' 
  AND token = 'GuxBAZZi77V+45bbTB6NYOAm4KS2ECJXG1C3F1Xx/y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}