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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b59105e0a3d7a371c899a15d6f24aeb0bc80d977ae17821d2bea12e20ec69ca' 
  AND token = 'qTyoAbklgPjILiRYApcj64CVcvdXGSNABQa0/wupui8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}