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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '669beb67b1f6932d15e11fbf7afe31fa0b2dd3842c444ce3bad7b02f79e1925e' 
  AND token = 'xEtkj9SG3aYISS2azgmjvMEYUl+y9Ga0ZWfFnRiVRBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}