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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21ed62f4d186eba787bc12b041b7b2d55b031917d861383e3c4eecb72c5d6c15' 
  AND token = 'Gt4gnzQr7usqOV9iafkXeOKAbC9xn2wpOPsZc5d6rwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}