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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac7d23971c995605617f9a7f000f60f54cc5b345525074c8480558d330634224' 
  AND token = '+UXYQjMj1c9j8iuJW1lGomChtIZr56fSKoIQMIZSiRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}