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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40d733bf4c89bfe6f3eba9f68ebeec771375cf2bfbafe6cb1b0549777b0a188a' 
  AND token = '+nNRRreqS7wbkKt3wswQx59VmurlmGkeXdRm+d6LpOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}