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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1aaf111effbbf360804c995a76b16900a14b9ca96d1be6008bac36acd206b09' 
  AND token = 'HRV0AzaU0brrAsIH32iZfITRnI2zbDB5CyogA21/kQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}