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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3f9118c247d5b0c958aaeb2e672bfb9202a913ea4b684a1abecbbdbaf82b7b9' 
  AND token = 'GlEXPwZ3B0veTZgG0f6xjwZD8ZLUT7ZOANh68V8BZ+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}