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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5989d42ff097d52ec19eee2886b491ff3c470d1f47f273a841624ca5a8f47f1d' 
  AND token = 'qUpOQuFUSBbbGqQ9d3Ue88NgSR5EuK7bida9J2QIw0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}