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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1efec73cae19a7447c9a3eb167164ce550af0907dfde88b6e8497480cbc1b1d5' 
  AND token = '1Gy/UOWroX3C6FcjFeZvu0zvz5zKuAkVG7BAnyMUXbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}