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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eb20959699c5c259dbbec0bca34a530d1df31ed8f161017911f7f90bf5712d3' 
  AND token = 'NmXbe/Aw2vt90JO0WNCg3fmY9nWceCfcPV9j65wv5as=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}