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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e5308a4c2e6a355289571fe10f17cd37c303332cd206d5dce496191ac8e3606' 
  AND token = 'wTPOiMj3K5XGsduRBInuXDph9k/HG9B2H8foyck4FW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}