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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6330e5d91f956debdfb3f01fc6323ef20e807fca038b31af8b0e7eb5b5b0a871' 
  AND token = 'DF6bNgscFIHRYUVtllgsuIdB6xM6u2LOT8+m9s8vzq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}