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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3e7a457a992ce288970254823b475b3ea6717ad13b9bc31a4d0d345cb585357' 
  AND token = 'uDAhey22/3oBw7o+fT8LeT0YXU6eE4wnpqk5VhzArWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}