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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c546b65ed8e9f885cd02621b9acd3f458af761bb9264520f3b78a042c63127f2' 
  AND token = '1+YbrLZWsn0CCy9PzNcat8K1Nxmr/Z86wlbOBp/vdP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}