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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b9e4188bf41cd60b8944d60b91ce0053e08e1fa2160be3ca687271dadaf68f4' 
  AND token = 'MaVVmku102n8TMz4YvvXz80ICcWN6xxIbvSeLt7lnE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}