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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06b073ad38e6bf33bb4f70f91bb4ddeac44400037c0f2319608f1f21bae64444' 
  AND token = 'qCIsKDQZHLk/1F1BYZjJo+C9WR30U1YXJIIcJGfiHuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}