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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '282badec2150f6f7c603062cbf4e6121cb076ad984dc5e0021a0fd113aff8a9e' 
  AND token = 'IkwB6TM5MqfhbDCfM+WH1x3TRuUXUs24qHiOjr6NGnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}