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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cee4cba4c82e6dc6e0f98b89ef30f83a7916135ef379d901c442fdc3db5894d9' 
  AND token = 's+kI1vUKXd+g+3+V8pY1qo0DzVQBt9ox1P5xXi2Y0/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}