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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d93fb506b5e52a556a687343dd80b521bacba7a5bc0a8ebbd852cbc9aedbd00' 
  AND token = 'QfUECkKdZv+ES3W4TCWay/eYs0SafcGsXSbcNKk+IwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}