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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc22e7171b08e8c2f553726cf6474848dd87db66be93b06e27267d9b8f450fcd' 
  AND token = '9rPgeFSxJLSF9yb+JImVJkvl/Ms8lPCA9yWsDZGAUPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}