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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a2d2532968d522e1022ca07a5352caea6765be48da457cdd51316742c3457f3' 
  AND token = 'Tr+0ScFb3FsRpDTRpyRCR3YEP2z+iYdmrWh5sADAPTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}