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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c27255f7f808cb4c71a20630eff3e90de7f1430f462f709c23f1ab3eb8a4222' 
  AND token = 'o8hizWgbrBP33bTPC975txG6kB1YR5yLIf2bbPOVtxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}