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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2a946b81c4408bb1a3c110551ea02b34b613a5ed3812441e886a45d15b1db70' 
  AND token = 'zJ8ancQEw5NIdm780Zw4JPVlygSxz647g0MlbKz0Ypc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}