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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '822a1ee7794cc8d41f7afa83d6e751b08caabccd24d8a64adc38717d4b03dd39' 
  AND token = 'XMbPSPeKXxk3+JrgCrnCVOu7ZpqZhix85E7XV9Mwgkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}