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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78965bf60f0279813bdd02b6298241f729273665cdee1798b58a78f19d20b0e5' 
  AND token = '55MLzphsDKLtD/RrnSDTWPPfb2B/CmQtOJgpTJgjTpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}