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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6075ec4d4531c1428a1a4c631dc7336ef7f6d3945a100712114251f0d4398294' 
  AND token = 'owc0Jw0v6tmfLkJoeHMdvWjeUWaK3Dab21c3EOUbNSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}