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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '235bbf2121c68c6ebe7f863f808a38302f6ed64848b82646db8bdab5d25cb008' 
  AND token = '1qbkHcb2TnsHVTGsxjhCqkMVO4IuOjBGcyfv9K9xDx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}