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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09373f8787a27865a4dc633e05298cf71ea0abff98e5dfe0a2e90fc2fa205fc7' 
  AND token = 'LHB2KZR1U0fZN3HkzdhVIxAqeRYfu1cOtNVw6OmZB0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}