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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c9ce3733b97685836407360950a4a27705a2676d3fb57bf4c9e9e0c27ca07c5' 
  AND token = 'bqYhV9Bk95Xip9ZeSl0wer8hA4ZAhwhuwwPtiAZGNng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}