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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '31e1f727eb688843d4fce0a67cec1904260d070c0cbbddf4bcdaf78ffe1e988b' 
  AND token = 'GXM05D4qXrjuCm/M/oiKAluFwOJxCeDzivy+uMQhRPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}