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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '111b540b917551842961c8d5fc21acdf8b9ec06b2671b9723cf17d1b484b169b' 
  AND token = 'McWb1s4YxdJmy4Kv+pAL23/zjEZrLe6cz7MVjvyl6DM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}