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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3549059579d15e5b7e27a8cb8ebc50988a61b2f919df45ffb773b3ea9ec30670' 
  AND token = '+zssxAj7cF6Ohz6qsncP19hcdJ7pUcWWm+HaXrUTRTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}