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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c4ca9d1a8ddb303fc7348de4a8c9c9f53a3d8062a4984416085e25ca780a40d' 
  AND token = 'xdrkVcRK7fLTFfUuVgOQmyKkDVJtWb6kh/LLABdUW9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}