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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd16b6f32b66577a0247dd01341f833ebf44c8ef6bdf11932c270788dc281b55f' 
  AND token = '+ELzRWKoR7ZjXWO9RHu2z1m7pC1xpcpwU+9vbfW235Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}