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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af88b7b6e585d52465524bdd33e03ba1dc4cc2aab1b799115a1981561f6ca22d' 
  AND token = 'aax48amcMHyQVwYsLe0vYq//dlnzcaSw5BD4XJsqNPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}