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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4544d5810f5bec65c30ca0e77cd3a832378a348c61c4036231757a1695a610a4' 
  AND token = '5GTFKh2n/rLbC3OD2rkbngfGy2GUk0Sz25zQwO+QMjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}