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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16ff394d888f4acf473c476d1daeaf8782606617551f515c895f5af74de6659e' 
  AND token = 'SxEHkTYqrsRkvlZ6sbPTbI35amelTOVt4ipmg2egCWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}